The true kings of the South generally weren't what most of us would call garage bands. They were groups like the Swingin' Medallions, Uniques, and the Tams -- huge regional acts that made occasionally national breakthroughs, but were as big as the English superstars in the South. I can tell you that the top band in Florida in '65-'66 was the Roemans. Today we wouldn't put them on the same pedestal as We The People or the Tropics, but thanks to their management and ties to Tommy Roe, they were THEE headliner.
It's hard to anoint a kingpin. Surely Little Phil & The Nightshadows were around long enough to be legends (and at 45+ members through the years, including Mac Davis, there are sure some stories to be told). The Gants are a great choice, but they were lucky to have a label that believed in them, and kept putting out albums, not just singles, despite each one selling worse than the one before. The Newbeats, Gentrys, Ronny & The Daytonas, and a few others also got the chance to keep putting out releases, with all of them moving into different musical waters by 1967. But the biggest kings of the South were able to rule the beach areas, from Panama City up to Virginia. It may seem hard to believe, but if I had to choose the most popular regional act of the '60s, it would be the Swingin' Medallions. They were thee kings of the beach dives, piers, and boardwalks of the South.